Nigel Perry

Research Leader, Plant & Food Research
Objective Leader, Nutrigenomics New Zealand

Research specialty: Natural products chemistry

Academic qualifications

1984 PhD, University of Otago, Chemistry.
1977 BSc, 1st Class Honours, University of Bristol, Chemistry

Distinctions/Honours

Fellow of NZ Institute of Chemistry
NZ Science & Technology Medal for excellence.
Assessor for the Royal Societh of New Zealand ISAT Fund
Member of NZBio, American Soc. Pharmacognosy, NZ Plant Protection Soc., Otago Institute of the Royal Soc. NZ; Advisory Board of Planta Medica
Referee for journals including J. Org. Chem., J. Nat. Prod. and J. Agric. Food Chem.

Employment Record

1991 to present Research Leader, Plant & Food Research
1993 to present Honorary Fellow, Department of Chemistry, University of Otago
1984-90 Post Doctoral Fellow, Dept of Chemistry, University of Canterbury
1977-79 Flavour Chemist, Spillers Ltd, Cambridge, UK

Key Publications

• Dayan FE, Singh N, McCurdy C, Godfrey CA, Larsen L, Weavers RT, van Klink JW, Perry NB 2009. β-Triketone Inhibitors of Plant p-Hydroxyphenylpyruvate Dioxygenase: Modeling and Comparative Molecular Field Analysis of their Interactions. J. Agric. Food Chem., 57: 5194–5200.
• Perry NB, Burgess EJ, Rodríguez Guitián MA, Romero Franco R, López Mosquera E, Smallfield BM, Joyce NI, Littlejohn RP 2009. Sesquiterpene Lactones in Arnica montana: Helenalin and Dihydrohelenalin Chemotypes in Spain. Planta Med., 75: 660-666.
• Chia EW, Pearce AN, Berridge MV, Larsen L, Perry NB, Sansom CE, Godfrey CA, Hanton LR, Lu G, Walton M, Denny WA, Webb VL, Copp BR, Harper JL 2008. Synthesis and anti-inflammatory structure-activity relationships of thiazine-quinoline-quinones: inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis. Bioorg. Med. Chem., 16: 9432-9442.
• Davidson MM, Perry NB, Larsen L, Green VC, Butler RC, Teulon DAJ 2008. 4-Pyridyl Carbonyl Compounds as Thrips Lures: Effectiveness for Western Flower Thrips in Y-Tube Bioassays. J. Agric. Food  Chem., 56: 6554-6561.
• Perry NB, Burgess EJ, Foster LM, Gerard PJ, Toyota M, Asakawa Y 2008. Insect Antifeedant Sesquiterpene Acetals from the Liverwort Lepidolaena clavigera.  2.  Structures, Artifacts and Activity. J. Nat. Prod., 71: 258-261.
• Svenson J, Smallfield BM, Joyce NI, Sansom CE, Perry NB 2008. Betalains in Red and Yellow Varieties of the Andean Tuber Crop Ulluco (Ullucus tuberosus). J. Agric. Food  Chem., 56: 7730-7737.
• Woollard JMR, Perry NB, Weavers RT, van Klink JW 2008. Bullatenone, 1,3-dione and sesquiterpene chemotypes of Lophomyrtus species. Phytochemistry, 69 1313-1318.
• Pearce AN, Chia EW, Berridge MV, Clark GR, Harper JL, Larsen L, Maas EW, Page MJ, Perry NB, Webb VL, Copp BR 2007. Anti-inflammatory Thiazine Alkaloids Isolated from the New Zealand Ascidian Aplidium sp.: Inhibitors of the Neutrophil Respiratory Burst in Gouty Arthritis. J. Nat. Prod. 70, 936-940.
• Durling NE, Catchpole OJ, Grey JB, Webby RF, Mitchell KA, Foo LY, Perry NB 2007. Extraction of phenolics and essential oil from dried sage Salvia officinalis. using ethanol-water mixtures. Food Chemistry 101, 1434-1441.
• Brennan NJ, Larsen L, Lorimer SD, Perry NB, Chapin EL, Werk TL, Henry MJ, Hahn DR 2006. Fungicidal sesquiterpene dialdehyde cinnamates from Pseudowintera axillaris. J. Agric. Food Chem. 54, 468-473.
• Mustafa K, Perry NB, Weavers RT 2005. Lipophilic C-methylflavonoids with no B-ring oxygenation in Metrosideros species Myrtaceae.  Biochem. Syst. Ecol. 33, 1049-1059.
• van Klink JW, Becker H, Perry NB 2005. Biosynthesis of irregular diterpenes in Anisotome lyallii by head-to-head coupling of geranyl diphosphate. Org. Biomol. Chem. 3, 542-545.
• Larsen L, Benn MH, Parvez M, Perry NB 2005. A cytotoxic triketone-phloroglucinol-bullatenone hybrid from Lophomyrtus bullata.  Org. Biomol. Chem. 3, 3236-3241.
• van Klink JW, Baek S-H, Barlow AJ, Ishii H, Nakanishi K, Berova N, Perry NB, Weavers RT 2004. Determination of the Absolute Configuration of Anisotome Irregular Diterpenes: Application of CD and NMR methods.  Chirality 16, 549-548