Angharad Morgan

Research Fellow, Department of Nutrition, University of Auckland
Leader - Genotyping, Nutrigenomics New Zealand

Research specialty: Genetic association studies

Academic qualifications

Bsc (Hons) Genetics, University of Manchester, 2000.
Phd, University of Southampton, 2004.

Employment record

2008-present Research Fellow, Department of Nutrition, University of Auckland
2005-2008 Research Associate, Department of Psychological Medicine, Cardiff University
2004-2005 Research Fellow, Centre for Research into Neurodegenerative Diseases, University of Toronto

Key publications

• Harold D, Abraham R, et al  (2009) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.  Nat Genet. 2009 Sep 6. [Epub ahead of print]
• Morgan AR, Hollingworth P, Abraham R, Lovestone S, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J. (2009) Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample. Am J Med Genet B Neuropsychiatr Genet. 150B(1), 61-64.
• Morgan AR, Hamilton G, Turic D, Jehu L, Harold D, Abraham R, Hollingworth P, Moskvina V, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan M, Powell J, Lovestone S, Williams J, Owen MJ. (2008) Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease.  Am J Med Genet B Neuropsychiatr Genet. 147B(6), 727-731.
• Morgan AR, Turic D, Jehu L, Hamilton G, Hollingworth P, Moskvina V, Jones L, Lovestone S, Brayne C, Rubinsztein DC, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J.  (2008)   Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet. 144B(6), 762-770.
• Abraham R, Moskvina V, Sims R, Hollingworth P, Morgan A, Georgieva L, Dowzell K, Cichon S, Hillmer AM, O'Donovan MC, Williams J, Owen MJ, Kirov G.  (2008) A genome-wide association study for late-onset Alzheimer's disease using DNA pooling.  BMC Med Genomics 1, 44.
• Hamilton G, Proitsi P, Jehu L, Morgan A, Williams J, O'Donovan MC, Owen MJ, Powell JF, Lovestone S.  (2007) Candidate gene association study of insulin signaling genes and Alzheimer's disease: evidence for SOS2, PCK1, and PPARgamma as susceptibility loci.  Am J Med Genet B Neuropsychiatr Genet. 144B(4), 508-516.
• Grupe A, Abraham R, Li Y, Rowland C, Hollingworth P, Morgan A, Jehu L, Segurado R, Stone D, Schadt E, Karnoub M, Nowotny P, Tacey K, Catanese J, Sninsky J, Brayne C, Rubinsztein D, Gill M, Lawlor B, Lovestone S, Holmans P, O'Donovan M, Morris JC, Thal L, Goate A, Owen MJ, Williams J.  (2007) Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Hum Mol Genet. 16(8), 865-873.
• Sato C, Morgan A, Lang AE, Kawarai T, Salehi-Rad S, Meng Y, Ray PN, Farrer LA, St George-Hyslop P, Rogaeva E.  (2005) Analysis of the Glucocerebrosidase Gene in Parkinson’s Disease.  Movement Disorders 20(3), 367-370.
• Edwards-Lee T, Ringman JM, Chung J, Werner J, Morgan A, St George Hyslop P, Rogaeva E, Hardy J.  (2005) A Large African American Family with Very Early Onset Alzheimer’s and an APP (T714I) Mutation. Neurology 64 (2), 377-379.
• Pearce E, Tregouet DA, Samnegard A, Morgan AR, Cox C, Hamsten A, Eriksson P, Ye S.  (2005) Haplotype effect of the Matrix Metalloproteinase-1 gene on risk of Myocardial Infarction.  Circulation Research 97, 1070-1076.
• Groen JL, Kawarai T, Toulina A, Rivoiro C, Salehi-Rad S, Sato C, Morgan A, Liang Y, St George-Hyslop P, Lang AE, Rogaeva E.  (2004) Genetic association study of PINK1 coding polymorphisms in Parkinson’s Disease. Neuroscience Letters 372(3), 226-229.
• Rogaeva E, Johnson J, Lang AE, Kawarai T, Gulick C, Gwinn-Hardy K, Sato C, Morgan A, Werner J, Nussbaum R, Petit A, Okun MS, McInerney A, Mandel R, Groen JL, Fernandez HH, Postuma R, Foote KD, Liang Y, Reimsnider S, Tandon A, Hardy J, St George-Hyslop P, Singleton AB.  (2004) Analysis of the PINK1 gene in a large cohort of cases with Parkinson’s Disease. Archives of Neurology 61(12), 1898-1904.
• Morgan AR, Rerkasem K, Gallagher PJ, Zhang B, Morris GE, Calder, PC, Grimble RF, Eriksson P, McPheat WL, Shearman CP, Ye S. (2004) Differences in matrix metalloproteinase-1 and matrix metalloproteinase -12 transcript levels among carotid atherosclerotic plaques with different histopathological characteristics.  Stroke 35, 1310-1315.
• Morgan AR, Zhang B, Tapper W, Collins A, Ye S. (2003) Haplotypic analysis of the MMP-9 gene in relation to coronary artery disease. Journal of Molecular Medicine 81, 321-326.