Dr Janine Cooney is a chemist at HortResearch and runs the HortResearch LC-MS facility.She has a strong background in chemical characterisation, specialising in LC-MS of small molecules, peptides and proteins with particular emphasis on proteomics and NMR spectroscopy. Other research interests include the chemical identification, microbial biotransformation and mode of action in biological control systems of fungal secondary metabolites, development of analytical methods including ELISA and the synthesis of molecularly imprinted polymers (MIPs) for isolation, selective sorption and sample enrichment of selected analytes.
Janine is part of both the Nutrigenomics Objective 3 and 4 teams. Her main role in both objectives is compound identification using LC-MS.
McGhie, T.K., Ainge, G.D., Barnett, L.E., Cooney, J.M. and Jensen, D.J. 2003: Anthocyanin Glycosides from Berry Fruit are Excreted Unmetabolized by Both Humans and Rats. J. Ag. Food Chem. 51, 4539-4548.
Cooney, J.M., Jensen, D.J. and McGhie, T.K. 2004: LC-MS Identification of Anthocyanins in Boysenberry Extract and Anthocyanin Metabolites in Human Urine Following Dosing. J. Sci. Food Agric. 84, 237-245.
Laing, W., Bulley, S., Wright, M., Cooney, J., Jensen, J., Barraclough, D. and MacRae, E. 2004: A highly specific L-Galactose-1-Phosphate phosphatase on the path to ascorbate biosynthesis. Proceedings of the National Academy of Sciences USA. 101, 16976-16981.
Klages, K.U., Boldingh, H.L., Cooney, J.M. and MacRae, E.A. 2004: Planteose is a short-term storage carbohydrate in Actinidia leaves. Functional Plant Biology 31, 1205-1214.
Cooney, J.M., Lauren, D.R., and Perry-Meyer, L.J. 1997: A novel tubular bioassay for measuring the production of antagonistic chemicals produced at the fungal/pathogen interface. Letters in Applied Microbiology 24, 460-462.
Cooney, J.M., Lauren, D.R., Poole, P.R. and Whitaker, G. 1997: Microbial transformation of the Trichoderma metabolite 6-n-Pentyl-2H-pyran-2-one (6PAP). Journal of Natural Products 60, 1242-1244.
Cooney, J.M. and Lauren, D.R. 1999: Biotransformation of the Trichoderma metabolite 6-n-Pentyl-2H-pyran-2-one (6PAP) by selected fungal isolates. Journal of Natural Products 62, 681-683.
Cooney, J.M., Hotter, G.S., and Lauren, D.R. 2000: Biotransformation of the Trichoderma metabolite 6-n-Pentyl-2H-pyran-2-one (6PAP) by suspension cell cultures of Pinus radiata. Phytochemistry 53, 447-450.
Petcu, M., Cooney, J., Cook, C., Lauren, D., Schaare, P. and Holland, P. 2001: Molecular imprinting of a small substituted phenol of biological importance. Analytica Chimica Acta 435, 49-55.
Cooney, J.M., Lauren, D.R. and di Menna M.E. 2001: Impact of competitive fungi on trichothecene production by Fusarium graminearum. J. Ag. Food Chem. 49, 522-526.