In order for the genes in our body to carry out their function, the â€œmessageâ€ contained within each gene must first be read. This process generates a so-called messenger (m)RNA â€œtranscriptâ€. Measuring transcripts provides important information on which genes are active at a particular time.
The simultaneous measurement of all active mRNA transcripts within a sample (using high-throughput technologies such as microarrays) is known as â€œtranscriptomicsâ€. This information provides a global picture of which genes are active at that time. As the function of many genes is already known, knowing which are active can be vital to understanding how a food influence the expression of key genes to produce an anti-inflammatory effect.
Capability: Expertise in measuring changes in expression levels of key genes in response to inflammation and/or dietary intervention, using microarrays and other high-throughput technologies.